How to Cite
Abstract
Two months ago, a television producer asked me to comment on a news story published by an AI-generated news network. Upon reviewing the story, I realized it was based on the results of the CREST-21 study published in the New England Journal of Medicine.
References
Brott TG, Howard G, Lal BK, et al. Medical management and revascularization for asymptomatic carotid stenosis. N Engl J Med. 2025 Nov 21. https://doi.org/10.1056/NEJMoa2508800
AbuRahma AF, Schermerhorn ML, Calligaro KD. Commentary by the Society for Vascular Surgery regarding CREST-2. J Vasc Surg. 2025. https://doi.org/10.1016/j.jvs.2025.12.090
AbuRahma AF, Avgerinos ED, Chang RW, et al. Society for Vascular Surgery clinical practice guidelines for management of extracranial cerebrovascular disease. J Vasc Surg. 2022;75(1 Suppl):4S-22S. https://doi.org/10.1016/j.jvs.2021.04.073
AbuRahma AF, Avgerinos ED, Chang RW, et al. The Society for Vascular Surgery implementation document for management of extracranial cerebrovascular disease. J Vasc Surg. 2022;75(1 Suppl):26S-98S. https://doi.org/10.1016/j.jvs.2021.04.074
Poorthuis MHF, Solomon Y, Herings RAR, et al. Temporal trends and determinants of stroke risk in patients with medically treated asymptomatic carotid stenosis. Stroke. 2023;54(6):1735-1749. https://doi.org/10.1161/STROKEAHA.122.041921
Howard VJ, Meschia JF, Lal BK, et al; CREST-2 Investigators. Carotid revascularization and medical management for asymptomatic carotid stenosis: protocol of the CREST-2 clinical trials. Int J Stroke. 2017;12(7):770-778. https://doi.org/10.1177/1747493017706238
Kakkos SK, Kakisis I, Tsolakis IA, Geroulakos G. Endarterectomy achieves lower stroke and death rates compared with stenting in patients with asymptomatic carotid stenosis. J Vasc Surg. 2017;66(2):607-617. https://doi.org/10.1016/j.jvs.2017.04.053
Saratzis A, Naylor R. 30-day outcomes after carotid interventions: an updated meta-analysis of randomized controlled trials in asymptomatic patients. Eur J Vasc Endovasc Surg. 2022;63(2):157-158. https://doi.org/10.1016/j.ejvs.2021.10.029
Halliday A, Bulbulia R, Bonati LH, et al; ACST-2 Collaborative Group. Second asymptomatic carotid surgery trial (ACST-2): a randomized comparison of carotid artery stenting versus carotid endarterectomy. Lancet. 2021;398(10305):1065-1073. https://doi.org/10.1016/S0140-6736(21)01910-3